domingo, 5 de octubre de 2008

Información desde Australia

Texto en inglés y español extraído de la pagina web de el Australian Bone Marrow Donor Registry.

Me gustó que la información es breve, concisa y directa siento que en Latinoamerica nos hace falta crear sitios con un formato parecido, me parece más amigable y accesible.
A continuación el texto en inglés, abajo la versión español cortesía de "moi" así es que si encuentran algun error haganmelo saber que soy principiante en esto de la traducción.

Patient home

What happens in a bone marrow transplant
To test the compatibility of a donor’s marrow with a patient’s marrow, a small sample of blood is drawn from the potential donor and patient. A human leucocyte antigen (HLA) tissue typing test is performed to determine if the antigens or markers on the white blood cells of the donor match those on the patient’s white blood cells.
Each person’s bone marrow has distinct genetic characteristics, half of which are inherited from their mother, the other half from their father. A patient with an identical twin has a ready made donor of perfectly matched bone marrow. Many however, will need to find another person related or unrelated, whose bone marrow matches their own.
In a bone marrow transplant, the patient’s diseased bone marrow is destroyed and healthy marrow is infused into the patient’s bloodstream. In a successful transplant the new bone marrow migrates to the cavities of the large bones, engrafts and begins producing normal blood cells.
The new bone marrow infused into the patient must match the genetic makeup of the patient’s own marrow as perfectly as possible. If the new bone marrow is not a good match, it will recognize the patient’s body as foreign material to be attacked and destroyed. This condition is known as graft versus host disease (GvHD), and can be life threatening.
When is a transplant possible
A successful transplant not only requires matched bone marrow but a patient who is healthy enough to undergo the transplant procedure. A medical physician will determine whether a patient should undergo a transplant, by examining the patient’s
general physical condition
diagnosis, and
the stage of the disease
After the patient’s marrow has been destroyed, healthy marrow is infused into the patient’s bloodstream over several hours. Unlike other transplants, a bone marrow transplant is performed in the patient’s hospital room.
It may take 3 to 4 weeks for the new bone marrow to engraft and begin producing healthy blood cells. The patient remains in the hospital until a sufficient number of healthy new red blood cells, white blood cells, and platelets are being produced by the new bone marrow. It usually takes 4 to 8 weeks before the patient’s immune system is able to defend itself against infection and bleeding.
Complications a bone marrow recipient can experience
In addition to the side effects caused by chemotherapy and irradiation such as nausea, vomiting, hair loss, diarrhoea, and poor appetite, there are several complications that may result from the transplant. These include:
rejection
Graft versus host disease (GvHD)
infection, and
relapse
Texto de: http://www.abmdr.org.au/patient_home.php?id=13

AHORA EN ESPAÑOL!

Patient home


Que pasa en un trasplante de Médula ósea
Para probar la compatibilidad de la medula de un donadora con la del paciente, una pequeña muestra de sangre es extraída del posible donante y del paciente. Un test de tejido de antígeno leucocito humano (HLA) es realizado para determinar si los antigenos o “markers” en las células blancas de la sangre del donadora son compatibles con las del paciente.
La médula ósea de cada persona tiene características genéticas distintas, la mitad de estas es heredada por la madre y la otra mitad del padre. Un paciente con un hermano gemelo idéntico tiene un donador hecho a su medida cuya médula ósea es compatible de manera perfecta. Aunque muchos, necesitaran encontrar a otra persona familiar o no relativo, cuya médula ósea sea compatible con la suya.
En un trasplante de médula ósea, la médula del paciente es destruida y se trasfunde médula nueva y saludable en el torrente sanguíneo del paciente. En un trasplante exitoso la nueva médula migra hacia la cavidades de los huesos grandes, se planta y empieza a producir células sanguíneas normales.
La nueva médula ósea trasfundida al paciente debe de encajar lo más perfectamente posible con la información genética de la médula del paciente. Si la nueva médula no es totalmente compatible, reconocerá al cuerpo del paciente como material externo que debe ser atacado y destruido. Esta condición es conocida como enfermedad de “injerto contra anfitrión” (GvHD Revisar definición exacta en español) y pone en riesgo la vida.
Cuando es un trasplante possible

Un trasplante exitoso no solo requiere médula ósea compatible si no también a un paciente que este lo suficientemente sano como para pasar por un procedimiento de trasplante. Un doctor determinara si el paciente debe o no someterse a este procedimiento através de examinación.
Condición física general
Diagnostico y
La etapa de la enfermedad
Después de que la médula del paciente ha sido destruida, médula sana es trasfundida en el torrente sanguíneo del paciente durante varias horas. A diferencia de otros trasplantes, un trasplante de médula ósea es hecho en el cuarto de hospital del paciente.
Puede tomar de 2 a 4 semanas para que la nueva médula ósea se plante y empiece a producir células sanguíneas sanas. El paciente permanece en el hospital hasta que un número suficiente de glóbulos rojos, glóbulos blancos y plaquetas nuevos y saludables han sido producidos por la nueva médula ósea. Usualmente el sistema inmunológico del paciente toma de 4 a 8 semanas para poder defenderse contra infecciones y sangrados.
Complicaciones que el receptor de médula ósea puede experimentar
Adicional a los efectos secundarios causados por la quimioterapia y radición, como son las nauseas, vomito, pérdida de cabello, diarrea y poco apetito hay varias compicaciones que pueden resultar a partir del implante, tales como:
Rechazo
Enfermedad de Injerto contra Huesped (GvHD)
Infección y
Recaida
Espero sus comentarios como siempre, se aceptan críticas, aplauso, más información, quejas, felicitaciones DONADORES! Este Blog es de todos.
A continuación un link a la página para que le echen un buen vistazo, es buena.
http://www.abmdr.org.au/patient_home.php?id=13

Un beso Grande, Montse.

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